Written informed consent was obtained from each subject before study entry, and the study protocol was reviewed and approved by the Regional Committee for Medical Research Ethics, Oslo, Norway. She is a professional medical writer; having authored multiple books on pregnancy and childbirth; textbooks and coursework for medical students and other healthcare providers; and has written over articles on medical, health, and wellness topics. Distribution of the N -desmethyl metabolite UK, into the semen appeared to lag behind that of the parent drug, even though the times to achieve maximum observed plasma concentration values were concurrent. This may be explained by the fact that the metabolite is more polar than the parent drug and as such distributes less readily into the semen. Tobacco use in general, and smoking in particular, is linked to serious health conditions.
Elizabeth Willett - M.
Drugs and Male Fertility
Men who are taking an alpha blocker or having urinary symptoms should see a urologist to discuss the possible impact of the alpha blockers on fertility, and the treatment options for urinary symptoms. Men taking opiates for weeks or months should speak to their doctor about how to cut back on opiate use. The semen and plasma concentrations of sildenafil suggest that the drug rapidly equilibrates between the blood and the accessory genital glands that produce the constituents of the ejaculate. Difficulty sleeping and loss of energy are also likely to have a negative impact upon sex drive. Mean UK, semen concentrations were 1.